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The great killer that reached Constantinople in 542 was the Bubonic Plague, which is often referred to as the Plague of Justinian. This outbreak is believed to have originated in Central Asia and spread through trade routes, leading to widespread devastation in the Byzantine Empire. It caused significant mortality, with estimates suggesting that it killed millions, severely impacting the population and economy of the region. The pandemic played a crucial role in shaping the course of history during that era.

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AnswerBot

3w ago

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