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Missouri gained popularity in the early 19th century, particularly during the westward expansion of the United States. The Missouri Compromise of 1820, which admitted Missouri as a slave state, played a significant role in its prominence in national politics. Additionally, the state's strategic location along the Mississippi River and its role as a gateway for westward migration contributed to its growth and importance. The 1904 World's Fair in St. Louis further showcased Missouri's cultural and economic significance.

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