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Thomas Jefferson was not explicitly an advocate of the nullification doctrine as it is understood in the context of the 19th-century debates, but he did lay some groundwork for its principles. In his 1798 Kentucky Resolution, he argued that states had the right to declare Federal Laws unconstitutional. This idea later influenced proponents of nullification, particularly during the Nullification Crisis in the 1830s, but Jefferson himself did not promote a formalized doctrine of nullification in the way it was later developed.

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