The U.S. Senate refused Woodrow Wilson's wishes of having, The League of Nations.
The US Senate can refuse to confirm appointments to the Judicial Branch.
They felt that they didn't have a voice in the Senate.
The U.S. Senate has the authority to confirm or refuse presidential appointments. Specifically, the Senate reviews and votes on nominations for key positions, such as cabinet members, federal judges, and ambassadors. If the Senate votes against a nominee, the appointment is effectively rejected. This process serves as a check on the president's power to make appointments.
Wilson refused because Huerta had murdered Mexico's former leader Fransisco Medeo in a coup. Wilson refused on the grounds of his "moral" diplomacy.
According the United States Constitution, the US Senate can refuse the president's appointments. It can also reject treaties that have been agreed to by the president.
The Allies refuse to accept a negotiated peace settlement presented by the Central Powers because they could not trust in their willingness to fulfill the terms. Germany was in particular deemed untrustworthy.
The Legislative branch, specifically the Senate
The House of the Senate might refuse to assign a number to it.
He refuse to extend civil rights to African Americans
It was the tribunes who could veto the actions of the senate (or any other magistrate except a dictator) if they were not in the best interests of the people.
They rejected any treaty that included the league of Nations.
If you referring to the Christian song with the chorus; "I don't want to live like I don't care. I don't want to say another empty prayer. Oh I refuse to, sit around and wait for someone else, to do what God has called me to do myself. I could choose not to move; but I refuse!" The song is I Refuse by Josh Wilson.