Who is in charge of United State's Senate?

Answer 1

President of the Senate (The Vice President) Actually no one is 'in charge of' the Senate. If anyone has a responsibility to try to govern the Senate, it's the responsibility of the two leaders. Article 1 of the US Constitution says "The Vice President of the United States shall be President of the Senate, but shall have no vote, unless they be equally divided." This means that the VP would be the deciding vote were there to be a tie in votes, but is not 'in charge of' the Senate.

Answer 2

The Vice President of the United States is the presiding officer of the Senate and is in charge of it. However, the day-to-day operations of the Senate are overseen by the Senate Majority Leader and the Senate Minority Leader, who are elected by the members of their respective parties.