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William Clark is best known for his role as a leader of the Lewis and Clark Expedition (1804-1806), which was commissioned by President Thomas Jefferson to explore the newly acquired Louisiana Territory and find a route to the Pacific Ocean. Clark and Meriwether Lewis mapped vast areas of the West, documented various plant and animal species, and established relations with numerous Native American tribes. Their journey significantly contributed to the expansion and understanding of the American frontier, paving the way for westward expansion in the United States.

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