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No. An R4 can only emulate a game so long as you have the correct emulator that was designed to run on a DS and a ROM that can played played on that specific emulator. An R4 can only emulate ROMS. These include:

Nintendo DS (well duh!!)

Game Boy Advance

Original Game Boy/ Game Boy Colour

Nintendo 64

Nintendo Entertainment System (NES)

Super Nintendo Entertainment System (SNES)

Sega Master System

Sega Mega Drive

Sega Game Gear

Playstation Portable? (PSP)

Other kinds of games are ISO games. These are games that are to be played on an actual console such as:

Playstation 1

Playstation 2

Playstation 3

Nintendo GameCube (Can be emulated on a PC however. Google "dolphin gamecube emulator")

Sega Dreamcast

Xbox

Xbox 360

PC Games/ Games For Windows

Unfortunately, even the most powerful of DS flashcards can't emulate ISOs yet, so I guess we'll just have to see what the future holds!!

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