In fallout 3 do you ever see amata again?

Answer 1

After The Waters of Life there is a new Radio signal in the vicinity of Vault 101, the Vault 101 Distress Signal from Amata. She gives you a brief explanation on the events leading up to that day and gives you the password to open the vault door. The Trouble on the Homefront quest begins here.

Upon entering the vault Vault 101 Security Officer Gomez (or Officer Armstrong if you already killed Officer Gomez) confronts you and if you answer positively he will lead you to see Amata or the Vault 101 Overseer. This quest can still be done if you killed The Overseer earlier, as he will have been replaced by Allen Mack, Wally Mack's (member of the Tunnel Snakes Gang) father. Allen Mack is even more oppressive than Alphonse Almodovar.

Amata will mention the Vault is in trouble and needs your help to stop her father. There are multiple ways of accomplishing this - by force, by reason or by Speech skill. She pleads for you not to kill her father. Afterwards you will have one final talk with Amata and she will ask you to leave the vault forever. If you do leave without killing everyone the Trouble on the Homefront quest will end and the vault will close permanently.

If you complete the Trouble on the Homefront quest by destroying the Vault's reactor, there is a random encounter involving Amata and Enclave Soldiers. They will ask her for the location of Vault 101, which she will give to them. Afterwards, the Enclave Soldiers will open fire. She is most likely to get killed by the Enclave Soldiers, but if you get to save her she'll probably die sooner or later anyway. If you wish to save her, you can make her essential using the console. Even if you save her, Amata will run away from you, cursing you for the trouble you caused. If you lie to Amata about killing Mack, she doesn't curse you. She only says "How big can the world be?," tells you to leave, and runs away.

If you complete the Trouble on the Homefront quest by killing the Vault overseer and convince her it was your only choice, she will say "I'm sorry, you're a hero, and you have to leave", a homage to the original Fallout at the end where Vault 13's overseer says the same line. (Note: This occurs regardless of Overseer, but certain dialogue choices may avoid this line.)