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Topical administration offers several advantages, including localized treatment, which minimizes systemic side effects and allows for higher drug concentrations at the target site. It is also generally easy to apply and can enhance patient compliance. However, disadvantages include limited absorption for systemic effects, potential for skin irritation, and variability in drug penetration due to skin barriers. Additionally, certain formulations may not be suitable for all areas of the body or all types of medications.
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