Can't be answered withou knowing if you are referring to a rimfire or centerfire 22
No
Unknown
A VERY good handgun- for most puposes. Durable, reliable, accurate, and powerful.
Probably, almost certainly, the .600 Nitro Express is the overall most power handgun bullet. Let me alter this answer by saying the .600 Nitro Express is a rifle round that one company made a pistol for. The most powerful handgun cartridge is the 500 S&W Magnum.
The exact value of a 1910 Colt 22 caliber mini handgun would actually be highly dependent on a number of factors. Most importantly, the condition of the handgun.
Not even close. There are several more powerful handgun cartridges, not counting the single shot pistols that use rifle cartridges. While Dirty Harry may have proclaimed it to be "The most powerful handgun in the world"- it is not.
The most powerful handgun in the world has to be the Austrian Pfeifer-Zeliska .600 nitro express revolver, but the most powerful PRODUCTION handgun is the Smith & Wesson Model 500 revolver that shoots the .500 cartridge.The .600 Nitro Express Zeliska revolver is an Austrian single-action revolver produced by Pfeifer firearms. It is the largest handgun in the world, weighing in at 6.001 kilograms (13.230 lb) and having a length of 55 centimetres (22 in). The cylinder section alone weighs 2.041 kilograms (4.500 lb). The Zeliska is also the most powerful handgun in the world, producing a muzzle energy of over 6 kilojoules (4,400 ft·lbf). The weight of the gun helps control the recoil, making controlled shooting possible.
There are many handgun rounds that exceed the 44 mag. 454, 460, 500 to name a few.
Fairly certain it is the Thompson Contender .600 Nitro Express for production firearms.
No, not by a longshot (no pun intended). Almost all "major" caliber handguns are more powerful than the 9mm.
Rifle, shotgun, or handgun? The 10 gauge shotgun at close range would be very high on the list, as would some of the buffalo rifle cartridges, such as the 45-110. The .45 Colt revolver was possibly the most powerful handgun of the day.
The .500 S&W magnum is the most powerful handgun round commercially available.