What problem did Europeans face in the 1400s which made getting spices more difficult?

The first settlers in North America were from which area of the world? What region on the map below experienced a post-World War 2 communist revolution? What is the history of the word doozy? Which continent has the greatest number of british colonies? What roles did families play in a west African society? How does the Age of Exploration and the Columbian Exchange continue to impact the world today? What countries were a member of the central powers during World War 1? Why did the Suffragettes bomb David Lloyd-George's house? What was the largest land-sea-air operation in history? What happened in 2000 to the world? Who was the leader in the Storming of the Bastille? What increased the importance of Latin America? What country was formed to give a home to hundreds of thousands displaced Jews after World War 2? What were some plants found on the westward expansion? Does the world walk have a negative connotation? What major impact did Zeus have on the world? Even though the king of France claimed the lands explored by Verrazano and Cartier many years passed before France built its first settlement in the New World? What is shield tax called in the middle ages? What is the main industry in Leicester? Is Qin Shi Huang di's tomb considered art?