What side effects would you get in pups mating brother and sister dogs?

Answer 1

You can end up with pups with physical (congenital) defects, such as blindness, heart problems, too many toes, reproductive problems...the list is endless. Do not allow this to happen if it's in your control to do so. In the wild, Mother Nature has ways to prevent this from happening (preserving the gene pool).

AnswerMost likely if the dogs are brother and sister you will get a gene mutation, and this might result in the insertion, deletion, or substitution of the correct genes. AnswerHappens ALL the time with no crazy results.

Y-THINK-Y

I've had a mother and son dog mate, and they actually had the greatest batch of pups I had ever seen. To my knowledge there have been no crazy dogs.

My mother and son dogs mated with no strange effects either.

Mother and son technically can be bred because they share only HALF the same DNA, whereas siblings have the same DNA on both sides. So, you may not initially have problems, but you couldn't sell them for decent money, no one decent would buy pups bred like that. I work at a vet clinic in a small town, so I get to meet "backyard breeders" frequently. They usually sell these puppies without a health certificate or papers, the new owners are pissed because they paid for a dog they can't even breed because of its bloodline, or because of its congenital heart defect or hip defects, etc...

Answer 2

Inbreeding, such as mating brother and sister dogs, can result in genetic disorders, congenital abnormalities, reduced immune system function, and a higher likelihood of inherited diseases. This practice can also lead to a limited gene pool and increased risk of health issues in future generations.