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If by "castrated" you mean "neutered" like a cat or dog, you'll have to ask a vet that is experienced with exotics (guinea pigs are considered "exotics" in the vet world). Keep in mind that neutering a male guinea pig will prevent him from impregnating females, but will not change his aggression toward other males if he has any.

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14y ago

What else can I help you with?