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No the two interact. If you Google doxycycline you can find a pdf download all about it and it says these two medications should not be taken together.

Ask your doctor if it can be taken two hours apart, because sometimes they do that if drugs interfere.

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12y ago
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13y ago

In answer to CAN you take them both at the same time: yes. SHOULD you take them both at the same time: no. Both are depression treatments and even though St John's Wort is a herbal medicine rather than a drug, it could exacerbate the effect of the Zoloft. Talk to your medical practitioner first before contemplating this.

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Q: Can you take st johns wort and doxycycline at the same time?
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