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Yes, if covered tightly enough (air tight) to keep adequate oxygen from getting into to your lungs.

People pass out when enough oxygen can't get to their brains from the blood stream to keep fully functioning. If the oxygen gets used up and isn't replenished through breathing air in and out of the lungs, then you could pass out, and if deprived of oxygen for too long, you could have brain damage or even die from the lack of blood flow and oxygenation.

The same effect can come from choking or strangling or other types of airway obstructions that prevent proper blood flow to the vital organs. It is not good for your body to have even short periods of low oxygenation, so it is not something to do casually or on purpose.

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Q: If your nose and mouth are covered with hands will you pass out?
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