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Is cardiac hypertrophy genetic

Updated: 12/16/2022
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16y ago

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Some cases of hypertrophy are due to genetics, while others are acquired later in life. The genetic form is called hypertrophic cardiomyopathy, whose prevalence is 1/500 individuals. There are several causes, most (if not all) of which are due to defects in the genes that encode certain proteins that control contraction of heart muscle.

Acquired cardiac hypertrophy usually refers to hypertrophy of the ventricles, most commonly the left ventricle. Left ventricular hypertrophy is most commonly due to excess work being placed on the left side of the heart. In the United States, a common source of this excess work is high blood pressure (hypertension).

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