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Clozapine is not a tricyclic antidepressant, but rather an atypical antipsychotic medication.

Atypical antipsychotics differ from typical antipsychotics by the range of receptors that are modulated or affected.

Typical antipsychotics primarily inhibit Dopamine 2 (DA2) receptors. Atypical antipsychotics block a host of receptors, namely serotonin and dopamine, but also including alpha and histamine receptors in varying proportions.

The benefit of Clozapine is that there is a lesser degree of dopamine inhibition that is aimed at reducing certain side effects.

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Q: Is clozapine in the tricyclic antidepressant class of drugs?
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