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The first time an Rh- patient receives blood from an Rh+ donor, the Rh- patient will develop Rh agglutinins (agglutinins=antibodies) in the blood plasma. If the patient receives another Rh+ donation, it will cause agglutination, or clumping of the blood. The red blood cell membranes become leaky and hemoglobin pours into the blood. A possible cause is kidney failure due to excess hemoglobin at filtration sites.

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12y ago
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9y ago

If they are transfused with Rh+ Blood which doesn't cause huge issues the first time, they will develop Rh antibodies. Also, if an Rh- woman is having an Rh+ child, during gestation and birth the blood can 'mix' and antibodies can form.

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14y ago

under what condition might a person develop RH-blood antibodies?

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Q: Under what conditions might a person with Rh-blood develop Rh antibodies?
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