It is 262 miles according to Google Maps.
It is 260.12 miles according to MapQuest.
It is 508.26 miles according to MapQuest.
About 480 miles using I-44 and I-64.
It is 262 miles according to Google Maps.
Fule prices at Kirksville, MO
About 1,750 miles.
Google Maps estimates the driving time as 8 hours and gives the mileage as 477.
Driving distance: 257.29 miles / 414.06 kilometers - Time: 4:06 h
The driving distance between Houston, TX and Kirksville, MO is approximately 945 miles, and the estimated driving time is about 14-15 hours depending on traffic and route taken.
It is 283 miles according to Google Maps.
It is 260.12 miles according to MapQuest.