What is the cause of hemophilia?

Answer 1

Classic hemophilia is a genetic defect on the X chromosome (so it's "sex linked"), which caused a Factor VIII deficiency.

This mutation can be inherited, i.e. passed down though a family from one generation to the next, however nearly 1/3 of all genetic cases are due to random mutations that take place at the time of conception.

Since the liver is responsible for the production of the clotting factor proteins, hemophilia can also be acquired and not genetic. These cases, while less common, can be caused by things such as liver damage and specific medications.

Symptoms:

1. Very easily bruised
2. Prolonged nosebleeds
3. Excessive bleeding from biting down on the lips or tongue
4. Excessive bleeding following a tooth extraction
5. Excessive bleeding following surgery
6. Blood in the urine (called hematuria)
7. Bleeding in the knee, elbows, and other joints (appears as joint swelling that feels warm to the touch and normally causes weakness and stiffening of the joint)
8. Bleeding in the brain
9. Cuts seem to bleed longer than normal
10. Arthritic joints at young age

a recessive allele

Hemophilia is a genetic disorder (you inherit it from your parents) where some proteins that cause your blood to clot do not work. This leads to increased bleeding.

Hemophilia is a hereditary (acquired, in rare cases) condition caused by a VIII (Hemophilia A) or IX (Hemophilia B) clotting factor deficiency. Clotting factors work with platelets to clot blood.

recessive allele for the X chromosome

Hemophilia is a sex-linked allele that is found on the X sex chromosome and can be passed on to the offspring of parents who are either carriers or have the disease themselves. Because hemophilia is found on the X chromosome, males are more likely to get this condition than females are.

Nothing specific. its a genetic disorder and happens mainly to males. its a X chromosome recessive dis order.

The decrease or absence of factor VIII

AIDS is not man made.

Hemophilia is caused by a lack of enough clotting factor (8, 9, or 11).

There are two types of hemophilia. One is hemophilia A, and the cause is missing or low levels of clotting factor VIII (8). About 9 out of 10 people who have hemophilia have type A. The other type is hemophilia B. The cause of this is missing or low levels of clotting factor IX (9).

Answer 2

Hemophilia is a blood disorder in which the affected individual has difficulty forming the clots that stop bleeding.

Acquired hemophilia is caused by medications or medical conditions that have a side effect of decreasing the ability of an individual's blood to coagulate.

Traditional hemophilia is caused by the person's inability to produce enough of specific clotting proteins, or proteins that function correctly. The reason the body cannot produce these proteins correctly is because there is a mistake in the genetic code of that individual where the process for making these proteins is coded. (Imagine trying to make a cake if the recipe has been altered and it leaves out yeast, or swapped rice for yeast.) Since this is a genetic disorder it can be either inherited or the result of a mutation that takes place at the time of conception.

Answer 3

In a hemophiliac, their body does not generate enough platelets in the blood stream. Platelets are the part of the blood that form long strings when exposed to air. These fibers shrink as they dry and pull on the edges of the wound and each other. They form a patch over the wound to stop blood from leaking and keep dirt out. When the body does not produce enough platelets, the patient can hypothetically bleed to death from a paper cut.

Answer 4

They do not get it, they are born with it. Hemophilia is a genetic disorder found on the "X" chromosome. It is usually manifest in male offspring but carried "hidden" in the female line.

Answer 5

There is problem with the gene, which produces the clotting factor 8 or 9. This gene is carried by X linked chromosome. This is a hereditary disorder. At times there is mutation in the gene.