0
Evidence relating to the structure and properties of swine pepsinogen and pepsin has been reviewed and used to suggest a tentative two dimensional picture of the skeleton of these two proteins. When pepsinogen, a folded single peptide chain, is converted to pepsin, there is a profound change in the physical and chemical properties of the protein. In an as yet unknown manner, except that it is initiated by a peptic cleavage of the protein chain, a single enzymic site is formed. This site is made up, quite probably, of the secondary carboxyl group of glutamic acid or of aspartic acid and a tyrosine phenol group in close proximity so that they can form hydrogen or hydrophobic bonds with the substrate in some unique manner that permits hydrolysis to occur at an accelerated rate.
Wiki User
∙ 14y ago
Wiki User
∙ 13y agoWhen pepsinogen comes into contact with HCl, it is converted to pepsin.
Wiki User
∙ 11y agoPepsinogen is pumped to the stomach which has an acidic medium so it`s activated to active pepsin digesting the proteins into polypeptides.
Wiki User
∙ 12y agoThat would be HCl or Hydrochloric Acid.
Wiki User
∙ 14y agoHydrochloric acid (HCl)
Add your answer:
Earn +20 pts
What is the name of the inactive form of a protein splitting enzyme in the stomach?
pepsinogen
What is the source of pepsin?
Pepsin is an enzyme which is secreted by Zymogen cells of the stomach. First it is secreted in an inactive form called Pepsinogen. After that Hydrochloric acid (HCl) activates it into pepsin. FUNCTION:Its function is to hydrolyse the proteins to yield peptide.
Why don't protease digest stomach and small intestine?
The protease released in the stomach is pepsin. When it is released it's in an inactive form called pepsinogen. Hydrochloric acid (HCL) is also released. HCL actives the pepsinogen to pepsin so it can break down protein. Both HCL and pepsinogen are released from different cells in the glands so they don't combine until they are released into the stomach, this prevents them from eating away the stomach wall. ALSO the stomach secretes a coating of mucus from epithelial cells which helps protect the stomach lining from being digested by pepsin and HCL.
What enzymes perform major proteolytic activities in the digestive tract?
pepsin/pepsinogen in the stomach chymotrypsin/trypsin in the small intestine
In the stomach the protein is digested by?
That is a proteolytic enzyme. Name of the enzyme is pepsin. It is secreted as inactive pepsinogen, which become active when it comes in contact with the hydrochloric acid, in the stomach.
What are the function of the pepsinogen in gastric juice?
Gastric juice, as known is an acidic juice present in the stomach. Pepsinogen in gastric juice conveys it to convert the pieces of food into a thick paste which then continues on. ^_^
What prevents pepsin from destroying the cell walls in the stomach?
Pepsin is secreted as pepsinogen. Pepsinogen cannot eat the walls of the stomach. Now, pepsin is formed when pepsinogen binds to the hydrochloric acid (HCl) in the stomach. Once they are binded pepsin is formed. The second reason on why the stomach doesn't eat it's self is because of the alkaline mucus that suround the walls of the stomach.
Name 2 secretions the stomach makes and what do they do?
pepsinogen mucus
Pepsinogen is the precursor to the gastric enzyme for protein digestion and is secreted by the parietal cells?
it is secreted by stomach glands as an inactive proenzyme, pepsinogen, which is converted to pepsin by the cleavage of acid-labile linkages in the acidic (low pH) environment of the stomach.
What is the name of the inactive form of a protein splitting enzyme in the stomach?
pepsinogen
Gastrin secretes what?
pepsinogen (a precursor of pepsin) which helps humans digest, when activated by HCL.
What is the difference between pepsin and pepsinogen?
Pepsin is a powerful protein digesting enzyme which is far too dangerous in its active form so it is released in an inactive pepsinogen form by the cell and activated only in the digestive tract where it is required to be active.
What substances are acitively absorbed in the stomach?
Aspirin and alcohol are two substances that are actively absorbed in the stomach.
What is the function of HCI?
coverts pepsinogen to pepsin Destroys bacteria
What does the chief cell do to help the body function?
it creates pepsinogen which ultimately helps the body function
Secretes hydrochloric and acid pepsinogen to begin the chemical break down of food?
The stomach secretes hydrochloric and acid pepsinogen to begin the chemical break down of food.
Secretes Hydrochloric and acid pepsinogen to begin the chemical break-down of food?
The stomach secretes hydrochloric and acid pepsinogen to begin the chemical break down of food.
