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Liposomes are spherical-shaped vesicles that can be created from cholesterol and natural non-toxic phospholipids, and their structure is similar to cell membranes. Liposomes have attracted attention as a carrier system for therapeutically active agents, owing to their unique characteristics, including biocompatibility, self-assembly capabilities, scalability, as well as a broad range of physical and chemical properties. Liposomes have shown great therapeutic potential as carriers for payloads and for delivery to targeted sites, which has led to several liposomal formulations designed for the preclinic and clinical trials, with applications ranging from cancer chemotherapy to gene therapy.
Liposomes are used as models for artificial cells. Liposomes can also be designed to deliver drugs in other ways. Liposomes that contain low (or high) pH can be constructed such that dissolved aqueous drugs will be charged in solution (i.e., the pH is outside the drug's pI range).
Creative Biolabs provides services for the development of liposome pharmaceutical formulations for the pharmaceutical/biotechnology industry. We have strong and extensive expertise and years of experience in the field of drug delivery and lipid biophysics.
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∙ 10y agoA liposome is a biological entity that consists of an inner vesicle surrounded by a lipid bilayer. The liposome was designed to deliver nutrients and medications to bodily tissues.
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When was Journal of Liposome Research created?
Journal of Liposome Research was created in 1988.
What travels around the nucleus in the electron?
liposome
What structural feature of a cell membrane is missing from the liposome?
protein.
Could a liposome be used to deliver a hydrophobic drug?
Yes, in the phospholipid bilayer.
What are fusogenic liposomes?
A fusogenic liposome composition for delivering a liposome-entrapped compound into the cytoplasm of a target cell is described. The liposomes have an outer surface coating of chemically releasable hydrophilic polymer chains which shield hydrophobic polymers on the liposome outer surface. Release of the hydrophilic polymer chains exposes the hydrophobic polymers for interaction with outer cell membranes of the target cells to promote fusion of the liposome with the target cells. Also disclosed is a method for using the composition to deliver a compound to target cells, and a method for selecting suitable hydrophobic polymers for use in the composition.
What has the author Parthapratim Chandaroy written?
Parthapratim Chandaroy has written: 'Control of cell-liposome adhesion and liposome content release by thermally regulating polymer-lipid bilayer interaction' -- subject(s): Drug Delivery Systems, Liposomes, Polyethylene glycol
What is the function of a liposome?
Liposomes are nanometer size phospholipid vesicle containing aqueous phase inside its cavity. This hydrophobic phospholipid layer and the aqueous cavity can be used to load hydrophobic and hydrophilic drugs respectively.
What is an azotosome?
An azotosome is a theoretical nitrogen-based counterpart to liposome structures composed of acrylonitrile self-assembled membrane in a liquid methane bath.
What has the author Guru V Betageri written?
Guru V. Betageri has written: 'Liposome drug delivery systems' -- subject(s): Drugs, Liposomes, Vehicles
What is the medical use of liposomes?
Liposomes are used commonly in medicine these days. A liposome can be used somewhat like a vehicle for transfer of drugs or nutrients. Many drugs are considered liposomal drugs.
Who was the iPad designed for?
Who was the Ipad designed for? Answer: The Ipad was designed for everyone! If you like the Ipad then it is designed for you too! It is completely customizable.
When was the lamborghini designed?
Designed and built in Italy.
