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Most Doctors would try to avoid having you taking both as together they can thin your blood. However, should you need to take both, as ibuprofen (Naproxen) is an NSAID and reduces inflammation, you should take only 1000mg's of Tylenol (2 - 500mg tablets) and 2 Ibuprofen (2 - 500mg Ibuprofen) every 6-8 hours as needed for pain & inflammation.

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Q: When taking Tylenol and ibuprofen together should you lower the dosage of each?
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