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. They are so hard to kill because of their structure. They have a unique cellular structure. They have a hard outer coat surrounding the spore. This makes it hard for disinfectants to penetrate. There is a very thick layer beneath the coat call the cortex. This gives it resistance to heat. There is a germ cell wall under the cortex.Under the germ cell is the inner membrane and it is a permeability barrier against many potentially damaging chemicals.

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10y ago
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15y ago

"In Biology, a spore is a reproductive structure that is adapted for dispersal and surviving for extended periods of time in unfavorable conditions." -Wikipedia

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10y ago

When harsh conditions exist, the spores will enter dormancy, and will only resume activity or growth when favorable conditions exist.

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8y ago

The hard covering protects the spore inside, as does the hard shell of an acorn, for example.

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12y ago

hey have an outer shell

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Q: Why are microbial spores resistant to dessication?
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