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Why does drug tolerance occur?
Tolerance describes the phenomena that occurs when the body "gets used" to a medication being present in the body and therefore the body registers that chemical to be normal t…o exist in the body. When this happens the effects, intended and unintended, of the medication decrease.
Yes. Especially opiates, opiods, benzo's and alcohol.
Alcohol consumption interferes with many bodily functions and affects behavior. However, after chronic alcohol consumption, the drinker often develops tolerance to at least so…me of alcohol's effects. Tolerance means that after continued drinking, consumption of a constant amount of alcohol produces a lesser effect or increasing amounts of alcohol are necessary to produce the same effect.
The answer is increase in Smooth Endoplasmic Reticulum (ER). This is because as the cell responds to different drugs it receives, the amount of smooth ER and its detoxyfiying… enzymes increase, thereby increasing the rate of detoxification, and thus the body's tolerance to that particular drug. This means that higher and higher doses of that drug are needed to achieve an effect.
Increased dependency and tolerance basically means you'll need more of the given drug to the the same amount of high, and if you ingest the same amount you have been you won't… feel as high, because your body is getting used to/immune to it.Dependence is when you have become addicted to the drug and then have a real physical or psychological need for the drug to function. That is why when you quit you go through withdrawal and it is best not to quit cold turkey if you want to succeed.
it means you don't react easily to the drug. you need more than average amount to feel something.
Yes it can especially with opioid narcotics its called cross tolerance
It means someone requires a higher doseage of a drug to acheive the same effects.
Drug tolerance can increase the likelihood of drug overdose for several reasons: 1) A person addicted to a drug to which they've built tolerance may overestimate th…e amount of the drug they need to ingest to get high. For instance, a heroin addict might find they need more and more heroin to stay "well" as the months go by. They might assume that they can put off the effects of withdrawal by doing double the amount of heroin they did yesterday. This can lead to an overdose. 2) The other reason tolerance can contribute to overdose is if someone who has had a period of sobriety thinks they can use the same amount of a drug that they used before their sobriety. This is a very common cause of death amongst heroin users. Alcohol is one of the only drugs in which tolerance can lead to death, without the overdose. When a person becomes physically addicted to alcohol (usually will experience delirium tremens when they have had short periods of time without alcohol), they can die when they try to quit drinking. Often the alcoholic will have seizures and needs prompt medical attention to prevent death.
well tolerance means you arent affected by it so easily while withdrawel means you were addicted to somethong and u arent givin enough of it
This should answer your question: Enzymes of the smooth ER help detoxify drugs and poisons, especially in liver cells. Detoxification usually involves adding hydroxyl groups… to drugs, making them more soluble and easier to flush from the body. The sedative phenobarbital and other barbiturates are examples of drugs metabolized in the manner by smooth ER in liver cells. In fact, barbiturates, alcohol, and many other drugs induce the proliferation of the smooth ER and its associated detoxification enzymes. This, in turn, increases tolerance to the drugs, meaning that higher doses are required to achieve a particular affect, such as sedation. Also, because some other the detoxification enzymes have relatively broad action, the proliferation of the smooth ER in response to one drug can increase tolerance to other drugs as well. Barbiturate abuse, for example, may decrease the effectiveness of certain antibiotics and other useful drugs.
Tolerance and dependence of a drug is a trademark of addiction. The tolerance of a drug builds in which case a person needs more of the drug in their system. The dependenc…e on a drug, is the need for the drug in which to feel like you are living a normal life.
Yes, tolerance does occur with LSD. After repeated usage within a short span of time, increased amounts of LSD will be needed to achieve the same effects that lower doses prev…iously produced.
it can reduce the effect of the medication