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The body has 23 pairs of chromosomes. There are numbers 1-22, then the 23rd pair are the sex chromosomes. Females have two X chromosomes, making them XX, men have one X and one Y, making them XY.

The principle of a genetic disorder, let's call it "p", is that if someone has one normal, dominant chromosome "P" and one disease-causing, recessive chromosome "p", they are a carrier for the disease, but don't actually suffer from it (effectively the "P" overrides the "p").

Sex-linked disorders are carried on the X chromosome. If a woman inherits one normal X and one X with a recessive disease on it, she will just be a carrier, as she always gets two X's. Men on the other hand are XY, any disease they inherit on their X chromosome will present because they don't have another, potentially normal, X around to override the diseased one.

Hope this helps. :)

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Q: Why is it possible for a man to be a carrier with a recessive genetic disorder but not with a sex-linked disorder?
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How is a carrier different from a person who has genetic disorder?

A carrier means that you have the gene for the disorder, but because the gene is recessive (meaning that it only shows when you have two recessive genes) and you obviously have a dominant gene as well, you won't show the disorder. Someone who actually has the disorder has two recessive genes. D = dominant gene r = recessive gene Dr = carrier, no signs rD = carrier, no signs DD = not a carrier, no signs rr = has the disorder


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