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The answer is more complicated than chromosome number.

Offspring of a cross between Przewalski's horse (66 chromosomes) and the domestic horse (64 chromosomes) are trisomic (2n+1) just like mules, mollies and hinnys, yet they are not sterile.

The problem is that while horses and donkeys share much of the same genetic information, it is structured differently. Testicular meiosis is arrested in Mules and hinny stallions at the primary spermatocyte stage because of incompatibility of synaptal pairing between paternal and maternal chromosomes.

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Q: An ass has 64 chromosomes and a mule is a horseass hybrid Descibe why there will be a difficulty in meiosis in mules?
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when does the duplication of chromosomes occur?


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