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An uneffected woman whose father has hemophilia marries a man with hemophilia will the son have it to?
Wiki User
∙ 11y ago
Almost certainly no. Hemophilia cannot be passed from father to son. There is a very slight chance (almost incalculable) that a spontaneous mutation can take place and thus make the son turn out to be a hemophiliac himself. Using the the best guess from the CDC, nearly 1/3 of hemophiliacs are the result of a random mutation. the statistic of 1 in 5000 male births is also a CDC statistic, this would imply that the son would have approximately a 1 in 15,000 chance of having hemophilia and his father's genetics would have nothing to do with it.
Men and women each have 23 pairs of chromosomes. Women have two X chromosomes; men have one X and one Y chromosome. Hemophilia is an X-linked genetic disorder, which means that it's passed from mother to son on the X chromosome. If the mother carries the gene for hemophilia on one of her X chromosomes, each of her sons will have a 50% chance of having hemophilia.
Hemophilia affects mostly boys, although it's very rare: Only about 1 in every 5,000 boys is born with it. The disease can affect people of any race or nationality.
Wiki User
∙ 11y ago
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