The Israeli people and Iranian people are actually rather similar. They both are very cultured with a "European" disposition. They like to read and write, have on-average a high degree of commerce and education, and a strong feeling of a national historic narrative.
The governments and social organization of Israel and Iran, though, could not be more different. Israel is a secular Parliamentary Democracy, where all citizens, including minorities, have the right to vote for the political party that will best represent them. The governing authority forms through various coalitions of different parties which between them select a Prime Minister. Israel protects most basic freedoms such as freedom of speech, freedom from unwarranted searches and seizures, personal freedom (permission of homosexuality and abortions), trial by jury, and numerous other rights. Iran is an Islamic Republic which means that while it has a legislature, its power is strongly circumscribed by an unelected judiciary: the Supreme Council of Ayatollahs. These religious leaders have prevented basic civil rights by repressing minorities, banning freedom of speech and assembly, and executing individuals for violations of Islamic Law. They also have a veto over the candidacy of any politician running for office, meaning that they can effectively prevent any politician who wishes to push Iran in a different direction than they do. Iran has become increasingly religious and apocalyptic in its world view.
No. While Israel is part of the Fertile Crescent, it is not part of Mesopotamia, which is mostly in the modern nation of Iraq, but is also partly in Syria, Turkey, and Iran.
Iran and Israel are the two major regional powers in the Middle East, however, Israel has consistently maintained the top position. This has resulted in Iran wishing to take hegemony away from Israel and become the dominant power in the Middle East. To this end, Iran has supported the Syrian Alawite Government (Bashar Al-Assad), the Terrorist/Paramilitary Organization of Hezbollah, the Terrorist/Paramilitary Organization of Hamas, and several other groups intending to weaken Israel and its position. Iran has consistently stated that it believes that Israel is a cancer and must be wiped off the face of the map (even though they make it clear that "they will not do the wiping"). Using these secondary forces to oppose Israel makes it appear like Iran is a peaceful country since Iran did not declare war on Israel, Hezbollah did or Hamas did. It gives Iran an odd deniability. Israel has responded by killing Iranian nuclear scientists and consistently derailing Iran's nuclear program. Israel has focused its energy in defending its borders and trying to contain retaliation to its source, not the proxies.
US & Israel invades Iran
With the exception of Israel, Turkey, and Cyprus, every country in Southwest Asia is partially or wholly autocratic.
Israel and Iran and Turkey
Iran > Iraq > Israel.
Israel and Iran are two separate countries, with no overlap.
No. While Israel is part of the Fertile Crescent, it is not part of Mesopotamia, which is mostly in the modern nation of Iraq, but is also partly in Syria, Turkey, and Iran.
The Middle East. Mostly between Iran and Israel.
Iran.
Both Iran and Israel have a history of hostility with various Arab nations.
-- Western Israel is bordered by Egypt and the Mediterranean Sea. -- No part of Iran borders any part of Israel.
Asia
No
The distance between Jerusalem, Israel, and Tehran, Iran, is 967 miles, (1,556km).
Iran has threatened to wipe Israel from the map. Israel has declared its intention to defend itself and its people. Most contemplated Israeli military strikes on Iran are air strikes. When considering the Iranian topography and the fact that Israel has no ally bordering Iran except Azerbaijan, a land invasion is effectively impossible.
The Middle East. Mostly between Iran and Israel.