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At what viral load and CD4 count level would ART be recommended?
Wiki User
∙ 13y ago
This is quite a complicated question that depends on where you live and which treatments you can access.
Firstly, you need to be ready to start treatment, and understand the importance of adhering to treatment.
Secondly, it will depend on the guidelines in the country that you live.
Treatment guidelines from the WHO recommend starting when the CD4 count drops below 350. This is the case for the UK and many other countries.
The US guidelines recently raised this to starting at any count below 500, and some countries have followed this lead, while other think it is premature and is unsupported by sufficient clinical evidence.
If you have health complications (for example Heart disease or hepatitis C coinfection), this may be a reason to start higher than 500.
Some of the panel members on the US guidelines wanted to recommend treating everyone at any CD4 count.
Finally, if you live in a country which only has access to drugs associated with complicated side effects like d4T (stavudine), then it may be better to wait until 200, as the risks from earlier treatment outweigh the potential benefit from startgin a little earlier.
Wiki User
∙ 13y ago
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What does the viral load and CD4 count indicate?
The viral load is a measure of how much HIV is present in the blood. A high viral load count would indicate the person has many copies of the virus in their body. The CD4 count, on the other hand, indicates how many CD4 or T-helper cells the person has. CD4 cells are part of the immune system. When they are destroyed, their numbers drop. This is what the HIV virus does--it destroys CD4 cells. Therefore, if a person has a low CD4 count, that means that their immune system is not functioning well, if at all.
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