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Yes.

When a baby is born from two parents with 47 chromosomes, the chromosomes of each parent will split into 23 and 24 chromosomes. This makes three posibilities under conception:

1. 23 from mom and 24 from dad, or vice versa: There's a 50% chance for this, and this will give the baby 47 chromosomes, so it'll have Down syndrome like its parents.

2. 24 from each parents. In this case it won't work, because a human being can't possibly live with 48 chromosomes. So 25% chance that there won't be a baby that can possibly survive.

3. 23 from each parent. There's a 25% chance for this, which mean that the baby won't have down syndrome.

So overall: 75% chance for normal baby, because people with Down Syndrome are no less normal than other people. And 25% chance for a baby that can't possibly survive through conception, and that's what I would call an abnormal baby.

And if the baby do survive through conception, these are the odds:

2/3 chance that the baby will have Down Syndrome.

1/3 chance that it won't.

100% chance for a normal baby :)

Or maybe 0% chance for normal baby? Because normal is relative, right?

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