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Can a change of as few as one DNA base can cause a genetic disorder?
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∙ 7y ago
True
Heather Tremblay
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True or false changes of a few as one DNA base can cause a genetic disorder?
Yes.
Can a change in a nucleotide cause a disease?
By changing a gene's instructions for making a protein, a mutation can cause the protein to malfunction or to be missing entirely. When a mutation alters a protein that plays a critical role in the body, it can disrupt normal development or cause a medical condition. A condition caused by mutations in one or more genes is called a genetic disorder. So, yes.
This provides a way for allele-linked diseases in parents and pinpoint the genetic base of an inherited disorder?
allele testing
WHAT HAPPEN IF YOU CHANGE A SINGLE BASE CODON?
If one base in a codon was changed, this would be a point mutation. This may not cause any change in the structure of the protein, or it could be severely damaging. Since most amino acids have more than one codon, it's possible that the mutation would result in one of the other codons for that amino acid. In that case, there would be no change in the sequence of amino acids, and no change in the structure or function of the protein. A point mutation might also result in a codon that codes for a totally different amino acid, which can cause a genetic disorder. One example of a genetic disorder caused by a point mutation is sickle cell anemia. It's also possible that the point mutation could cause the codon to code for a stop signal. Please read the article in the related links for more information.
What happens if you change a single base in codon?
If one base in a codon was changed, this would be a point mutation. This may not cause any change in the structure of the protein, or it could be severely damaging. Since most amino acids have more than one codon, it's possible that the mutation would result in one of the other codons for that amino acid. In that case, there would be no change in the sequence of amino acids, and no change in the structure or function of the protein. A point mutation might also result in a codon that codes for a totally different amino acid, which can cause a genetic disorder. One example of a genetic disorder caused by a point mutation is sickle cell anemia. It's also possible that the point mutation could cause the codon to code for a stop signal. Please read the article in the related links for more information.
What genetic base can microcephaly have?
If the gene defect(s) are expressed during fetal development, the condition is present at birth. This is the congenital form of the disorder
A mutation is a change in the genetic coding of a gene.?
Yes. Change in the sequence of nitrogen base can be regarded as a mutation.
A change in the base subunit sequence during DNA replication can result in?
Many times a change in the base sequence during DNA replication will cause a mutation but if it is the 3rd base often there will be no mutation . It will often give the same protein. The term is genetic "wobble" and is seen when mRNA and tRNA match do not match at the third base.
What is the base word of the word disorder?
The base word of "disorder" is "order."
Which genetic change is best described by the following statement A random change in the base sequence of DNA results in an alteration of a polypeptide?
a mutation
How can a small change in a persons DNA cause a genetic disorder?
Some genes encode products that regulate the translation of other genes, or the activity of other proteins, so one small change will affect a lot of other genes/proteins. If that change affects something critical it might lead to a genetic disorder.
What are some types of genetic mutations?
Mis sense: change of a base resulting in a different amino acid Non sense: change of a base resulting in a stop codon Addition: extra base is added Deletion: a base is deleted Substituion: a base is replaced.
