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Sure. Single base mutation sometimes results in serious genetic disorder. For example, sickle-cell anemia come about when one base changes. The product,hemoglobins , though with only one amino acid different, would led to aggregation under certain circumstance.
Yes, a change in nucleotide bases in DNA can cause a disease. Diseases that occur from such changes are genetic diseases. These diseases are caused by mutations in DNA, which are basically changes in the nucleotide base sequence in the DNA.
If one base in a codon was changed, this would be a point mutation. This may not cause any change in the structure of the protein, or it could be severely damaging. Since most amino acids have more than one codon, it's possible that the mutation would result in one of the other codons for that amino acid. In that case, there would be no change in the sequence of amino acids, and no change in the structure or function of the protein. A point mutation might also result in a codon that codes for a totally different amino acid, which can cause a genetic disorder. One example of a genetic disorder caused by a point mutation is sickle cell anemia. It's also possible that the point mutation could cause the codon to code for a stop signal. Please read the article in the related links for more information.
The substitution of one base for another during DNA replication is an example of a point mutation. Depending on the substitution, this could be harmless, or it could cause a genetic disorder, such as sickle cell anemia.
If the gene defect(s) are expressed during fetal development, the condition is present at birth. This is the congenital form of the disorder
Many times a change in the base sequence during DNA replication will cause a mutation but if it is the 3rd base often there will be no mutation . It will often give the same protein. The term is genetic "wobble" and is seen when mRNA and tRNA match do not match at the third base.
Mis sense: change of a base resulting in a different amino acid Non sense: change of a base resulting in a stop codon Addition: extra base is added Deletion: a base is deleted Substituion: a base is replaced.
the order of base pairs are important because then the sequence of the genes will change, sending different genetic material
Sickle cell anemia causes sickle-shaped red blood cells. It is caused by a single base pair gene mutation.
For example adding a base.
A mutation in which an extra nitrogen base is added is called a frameshift mutation. The rest of the sequence after the mutation will code for different amino acids, which will result in the alteration of the protein. Frameshift mutations cause severe genetic disorders.
the base sequences signify what genetic code
The deletion of a single nitrogen base in a particular gene will cause the rest of the genetic code for that particular gene to become senseless, and the protein that is supposed to be formed from that code will be useless. If this occurs in a gamete, then the resulting offspring can inherit a genetic disorder, or may not even be able to survive very long after fertilization. If this happens in a body cell, a tumor, including a cancerous tumor could result.
Mutation of the genetic code causes DNA variation in organisms. For example, during DNA replication, one nitrogen base may be substituted for another, or an extra base can be added, or a nitrogen base can be skipped. If any of these mutations occur during the formation of gametes (sex cells), then the offspring that receives the mutation may have a genetic disorder.
A genetic mutation is any change in the base sequence of DNA. These changes can be an insertion, deletion, translocation (moved) or substitution of base pairs.Because of this change in the DNA sequence, a different or a faulty amino acid will be coded for. This can change chemical pathways. New alleles are created only through mutations and so it is a source for genetic variation in a population.Not all mutations are necessarily "bad", some may actually benefit the organism.
because pH was changed
No, because of the redundancy in the genetic code (several base triplets or codons code for the same amino acid) a point mutation, for instance, (a change in one base) may have no effect on the amino acid sequence in the protein, and so no effect on the expressed phenotype.
It just can. Even this tiny one base change can cause a mutation that is this severe. Many do not, but this one does.
a chnge in the sequence of base pairs
It is a direct - and exact - copy of the Genetic Sequence of the Dna; except that the base Thymine in Dna is replaced by the base Uracil in Rna.
When you change one or several nitrogenous bases it produces a change in the function of the protein. The reason why is because the amino acid that is being added to the protein changes due to the change of one of the base. So the shape will change and have a different function.Your Welcome,Anonymous
you can remove a person from the 3rd base and 1st base and then onto another field.You do not need to have a person on first or third base as this does not cause any rounders
The DNA acts as the genetic material because it acts as a code. The requirements for the complimentary base pairings ensures information doesn't accidentally change during the incredible number of cell divisions that happen each day.
DNA base sequences determine the protein. So if the sequence changes, then the protein can too.
Mutations can result from spontaneous events or external mutagens. A change in DNA sequence may change the pattern of protein folding, resulting in genetic disease. Some genetic diseases may be caused by the substitution of only one incorrect amino acid in a protein. It is possible for the substitution of one base for another to have no effect on an organism.