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All phase specific types are by definition cell cycle specific? But does it work the other way around? (i.e. are there any types that are only cell cycle specific but not phase dependent?)

Would like to now about the four main types of chemo.

Alkylating agents - cell cycle independent

Mitotic inhibitors - phase dependent?

Topoisomerase inhibitors - both phase dependent and/or cell cycle dependent?

Antimetabolites - phase specific?

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Q: Can chemotherapy be cell cycle dependent but not phase specific (ex. pls)?
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