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Only few studies have investigated wheatear use of clarithromycin during pregnancy is associated with miscarriage. Some animal studies have shown that rabbits and monkeys have increased rates of miscarriage when being exposed to clarithromycin during pregnancy (Biaxin product information). Adrienne Einarson and her colleagues observed in 1998 that women exposed to clarithromycin during pregnancy had a doubling in the risk of having a miscarriage. Recently Jon Andersen and colleagues found a 50 % increase of miscarriage in women exposed to clarithromycin in early pregnancy both compared to untreated and compared to women exposed to antibiotics used in same conditions.
The results indicate an association between clarithromycin and miscarriage.
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∙ 11y ago
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