Can you catch the same cold twice?

Catching the Same Cold Twice:

No, a cold is a viral infection, and once the virus has been in your system, you become immune to it if you have a healthy immune system. Therefore, if you are exposed to the same virus, it will have no effect because your body already has defenses built for it.

However, you can catch a second kind of cold virus after having a different kind before. The reason this happens fairly frequently is that common cold viruses mutate quickly into new forms. The virus may change only a tiny tiny bit, but technically, what you would be contracting causing a second cold is a mutated strain of the same cold virus, or a different one of the many hundreds of cold viruses around at any given time.

Your immune system makes anitbodies and has sort of a "memory card" so to speak, of the exact virus you had so that you can't get the same one again.

See the related question below for more detail about viral infections and the immune system.