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No. For one reason, you cannot go sublingually through a PICC line, as a PICC line would not be inserted sublingually. The most glaring issue however, is that oral morphine (which I think you are suggesting) can only be given orally. A PICC line is an intravenous route, and would therefore not be appropriate.

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Q: Can you give liquid morphine sublingual in a pic line?
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