Yes, it sure can. Have your tires inspected and balanced before assuming the drive shaft is the culprit. You may also have a bent wheel.
check u joints on driveshaft.
Tires out of balance, bent wheel, worn suspension or steering parts, bent driveshaft.
Wheel balance may be off...
Numerous reasons possibly dirty fuel injectors, if its a 4 wheel drive could be different sized tires. It can also be a tire out of balance, bent wheel, or bent driveshaft.
Wheels are out of balance
1. out of balance wheels 2. misaligned front end 3. worn out steering dampner.
Out of balance or damaged tire(s). Damaged wheel(s). Engine misfire. These are the three most common culprits.
Maybe its your motor mounts.
A universal joint on the driveshaft going bad.
Yes, either can cause a shake while driving.
A worn out Universal joint in the rear driveshaft.
Tire out of balance or a bent wheel. Also check the motor mounts; this model had problems with them.