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Frontline for cats and dogs are chemically very similar. Frontline Plus for cats contains 100g/L fipronil and 120g/L methoprene. For dogs Frontline Plus contains 100g/L fipronil and 90g/L methoprene. As such, using the dog version on a cat would result in a higher dose of fipronil and lower dose of methoprene.

Fipronil is an insecticide which disrupts insects central nervous systems, and is the portion which kills adult insects. Methoprene is an insecticide which disrupts the reproductive process, preventing larvae from growing into adults. The reason for the variation between the formulas is not clear, and there is not sufficient unbiased and non-anecdotal data to say what effects such slight mis-dosing can cause to the pets.

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12y ago
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11y ago

Frontline, Revolution and Advantage can all be safely used on cats and dogs interchangeably, as the ingredients are identical, you just need to know the correct doses.

Frontline Plus for Dogs contains (fipronil 9.8% and S-methoprene 8.8%)

whereas

Frontline Plus for Cats contains (fipronil 9.8% and S-methoprene 11.8%)

Dogs are given a dose of 0.067ml of Frontline solution per kilogram of bodyweight.

So a 10.0kg dogs need a dose of 0.67ml

an 6.0kg dog only really needs 0.40ml

ALL cats are given a set dose of 0.50ml

The Frontline Plus for cats formula contains exactly the same concentration of Fipronil (the main ingredient which kills fleas, ticks, and lice) as the Frontline Plus for dogs formula.

The only difference is the cat version contains 3% MORE of the ingredient methoprene than the dog formula.

Giving your dog a tiny 3% more methoprene will not harm it. Look up the toxixity of methoprene online for yourself and see.

Methoprene simply acts as a juvenile hormone analogue in fleas, it keeps the fleas "young". The flea larvae are prevented from completing the metamorphosis into adults and subsequently die.

Other Answer:

Frontline for cats and dogs only differs in the concentration of S-methoprene - which cats need more of. The weight differences may impact on the effectiveness of frontline.

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Q: Can you use frontline for cats on dogs?
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What to do if a cat encounter with Frontline for dogs?

Frontline for Dogs is not dangerous to cats (or Frontline for Cats to dogs). They are simply different doses of the same active ingredients (because of the species differences). Frontline for Dogs will still work on cats - but not at the same efficiency (towards the end of the month) as Frontline for Cats. Therefore you should always use the correct product for the species.


Can you use FrontLine plus for cats on a small dog?

Absolutely NOT- only use medication for dogs for dogs and medication for cats for cats!


Sentence with the word frontline?

Use Frontline on your dogs and cats to prevent fleas. I used frontline on Fido yesterday.


Can you use frontline on a horse?

No, Frontline is for fleas on dogs and cats. Horses get Lice. Use lousepowder. Frontline is likely it orritate the horses skin.


Can you put Frontline for cats and Frontline for dogs together on your dog?

I would not recommend it. I do know you should never put the canine Frontline on a cat. You should use the canine Frontline for the dog according to his weight and the same for a cat, use feline Frontline only. Why mix them?


Can frontline for small dogs be used for cats?

Check the front of the packet. Some of the spot-ones will say they are safe for dogs and cats. Some are definitely not safe for use on cats, e.g. Advantix.


What is the cost to use Frontline on cats?

The cost to use Frontline on cats can vary. Typically, the cost to use Frontline on cats ranges from the prices of fifty dollars to one hundred and sixty four dollars in the US.


Can you use frontline and a flea collar?

No. Frontline products should be used on the specified species. This is because one of the main components of Frontline, S-Methoprene is needed in a higher dose in cats. This is because it does not last as long in a cat than in a dog. So, if you used Frontline for dogs on your cat, it may not be as effective. However, this higher dose is still safe to use on a dog - so you could use Frontline for cats on a dog.


What products does Frontline have for cats?

Frontline's two products for cats are Frontline Plus, a flea/tick repellent, and OraVet, product for protecting pets' teeth. Frontline also sells products for dogs, like Heargard, which protects against heartworm.


Can you put frontline plus for dogs on a ferret?

NO, but you can use frontline plus for kittens on a ferret


Can you use Frontline for cats on a pregnant cat?

According to the documents on the Frontline website, Frontline Spot-On treatment is deemed safe to use on pregnant cats and kittens above 8 weeks old. If you are unsure, contact your vet.


What is the safest flea product for dogs?

It depends on the age of the puppy. But if i were you i wouldn't put flea treatment on them until they are at least 8 weeks of age. I use frontline plus on all of my dogs and cats.