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The amino acid sequence of the sickle cell allele for hemoglobin varies from the normal allele for hemoglobin by one amino acid. The sickle cell allele for hemoglobin has valine instead of glutamic acid. When the oxygen level of the blood decreases, the hemoglobin molecules come out of solution, stick together, and form long chains that cause the red blood cells to become sickle shaped.

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13y ago
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13y ago

Sickle cells are a sickle or crescent shape that can only carry a fractional amount of oxygen and nutrients. Normal cells are shaped like doughnuts.

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11y ago

You need to do this. It is clearly a class assignment. A good way would be to make a Venn diagram .

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Q: Compare the normal allele for hemoglobin with the sickle cell allele How does this difference affect the persons red blood cells?
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