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Could halothane alter synaptic function and cause a single action potential in a motor axon?
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What is the difference between action potentials and synaptic potentials?
A synaptic potential exists at the INPUT of a neuron (dendrite), and an action potential occurs at the OUTPUT of a neuron (axon). (from OldGuy)(from Ilantoren:) A synaptic potential is the result of many excitatory post synaptic potentials (epsp) each one caused by the synaptic vesicles released by the pre-synaptic terminus. If there are enough of these epsp then the responses will summate and depolarize the post-synaptic membrane at the axon hillock enough to fire an action potential.
A synaptic knob would be located on a?
A synaptic knob is a tiny bulge at the end of a terminal branch of a presynaptic neuron's axon!
What happens after nerve signal reaches a synaptic knob?
In general, action potentials that reach the synaptic knobs cause a neurotransmitter to be released into the synaptic cleft. The arrival of the action potential opens voltage-sensitive calcium channels in the presynaptic membrane.
Where do synaptic vesicles discharge their contents by exocytosis?
in the presynaptic membrane :)
Inhibitory postsynaptic potential is associated with what?
An inhibitory postsynaptic potential (IPSP) is a kind of synaptic potential that makes a postsynaptic neuron less likely to generate an action potential.
What causes calcium channels in the synaptic knob to open?
depolarization of the presynaptic membrane due to an arriving action potential
How does the nervous stimulus pass to the motor end plate?
An activated neuron will send an action potential from upper motor neurons to lower motor neurons to effector organs. It is able to propagate the action potential to the motor end plate by release of neurotransmitters, chiefly acetylcholine. On the terminal bouton the action potential opens voltage gated calcium channels. There is an influx of calcium in the pre-synaptic cell and it pushes the vesicles that contain acetylcholine. These vesicles will pass through the synaptic cleft and bind to cholinergic receptors on the post synaptic neuron. Each vesicle has a miniature end plate potential of 0.5mV. In a normal action potential, it will depolarize the post synaptic motor neuron from -85mV to approximately 0-15mV. So that's approximately 180 vesicles.* The influx of neurotransmitters (primarily acetylcholine) will depolarize the motor end plate and propagate the action potential. *Threshold of an action potential is approximately -55mV so technically the minimum required to continue an action potential is around 60 vesicles.
What happens when a neuron becomes excitable?
A neuron which is excitable is in its RESTING STATE, which means that it is POLARIZED, and thus able to be stimulated into an action potential.
When an action potential passes over the surface of synaptic knob the contents of vesicles is released in the presence of?
exocitocisThey dir
The electrical charge of an inactive neuron is known as?
Potential, ok well we all know it's a potential, but which one? Is it Action Potential, Synaptic Potential or Membrane Potential. Just saying Potential isn't saying much?
What determines if an action potential is initiated in the postsynaptic neuron?
Every time neurotransmitter is released from the presynaptic neuron it generates an excitatory post synaptic potential(EPSP) in the postsynaptic neuron. When the EPSP is greater than the threshold for excitation an action potential is generated.
What is the sequence of events in the process of synaptic transmission?
Neurons communicate with each other by sending electrical signals across a synapse. In a three neuron loop the series of events that happen in synaptic transmission are as follows: Neuron 1 sends an electrical signal (action potential) down its axon towards the synapse. The action potential causes the release of neurotransmitters (chemicals) from the terminal button of Neuron 1 into the synaptic cleft. The neurotransmitters bind to the receptors of Neuron 2. This binding triggers a new action potential in Neuron 2 which travels down its axon. The action potential causes the release of neurotransmitters (chemicals) from the terminal button of Neuron 2 into the synaptic cleft. The neurotransmitters bind to the receptors of Neuron 3. This binding triggers a new action potential in Neuron 3 which travels down its axon. The action potential causes the release of neurotransmitters (chemicals) from the terminal button of Neuron 3 into the synaptic cleft. The neurotransmitters bind to the receptors of Neuron 1 closing the loop.This series of events is repeated continuously allowing for the communication between neurons in a three neuron loop.
