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Every time neurotransmitter is released from the presynaptic neuron it generates an excitatory post synaptic potential(EPSP) in the postsynaptic neuron. When the EPSP is greater than the threshold for excitation an action potential is generated.

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Q: What determines if an action potential is initiated in the postsynaptic neuron?
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Inhibitory postsynaptic potential is associated with what?

An inhibitory postsynaptic potential (IPSP) is a kind of synaptic potential that makes a postsynaptic neuron less likely to generate an action potential.


Where do neurotransmitters that bind the postsynaptic membrane generate?

action potential


What is the result of inhibitory neurotransmission on the postsynaptic membrane?

Hyperpolarization of the membrane. This inhibits action potential generation.


How does the end plate potential differ from a EPSP on a post synaptic cell?

End plate potential is the change in potential from neurotransmitters. It can be excitatory or inhibitory. If the action potential wants to continue, it will be excitatory and vice versa. It can be additive, if more action potentials are fired it will increase the end plate potential. An action potential is an all or none response. It will either proceed or it will not proceed depending on the terms of the threshold. It cannot be additive, because there is an absolute refractory period where no additional action potentials can be fired.


2 Define refractory period and differentiate between absolute and relative refractory periods?

refractory period is the interval between action potential , the absolute refractory period is the period in which second action potential can not be initiated but in relative refractory period the second action potential can be initiated by the more strong stimulus.


What determines whether a neuron has an action potential?

epsp's & IPSP's


Which membrane potential occurs because of the influx of Na plus through chemically gated channels in the receptive region of a neuron?

An excitatory postsynaptic potential, a type of graded potential, occurs because of the influx of Na+ through chemically gated channels in the receptive region, or postsynaptic membrane, of a neuron. Graded potentials are generated by chemically gated channels, whereas action potentials are produced by voltage-gated channels.


What is the relationship between the action potential and the synapse?

A synapse and an action potential have a flip-flopping cause and effect relationship, in that an action potential in a presynaptic neuron initiates a release of neurotransmitters across a synapse, which can then subsequently potentially trigger an action potential in the axon of the postsynaptic neuron, which would then cause release of neurotransmitters across a following synapse.


What is the difference between presynaptic and postsynaptic neurons?

Presynaptic neurons release the neurotransmitter in response to an action potential. Postsynaptic neurons receive the neurotransmitter (and can however become presynaptic to the next nerve cell, if the neurotransmitter has stimulated the cell enough).


Series of events from the time the action potential reaches the persynaptic terminal to the activation of the postsynaptic receptor?

After the action potential reaches the presynaptic terminal, voltage-gated calcium channels open, leading to an influx of calcium ions. This triggers the release of neurotransmitters into the synaptic cleft. These neurotransmitters then bind to receptors on the postsynaptic membrane, leading to depolarization and the generation of a new action potential in the postsynaptic neuron.


A virus causes damage to the sodium channels of the postsynaptic neuron such that they open very slowly in response to a neurotransmitter How does this modify the generation of an action potential?

The sodium influx necessary for depolarization will occur more slowly making the action potential difficult to generate.


During which period can a second action potential be initiated by a larger than normal stimulus?

This the relative refractory period.