A protein consists of amino acids. Some of these amino acids are polar, having positively charged sides and negatively charged sides. A change in PH simply means a change in the amount of (H+) atoms. As you can see these hydrogen atoms are positively charged, and attract the negative side of the polar amino acids. so a change in the PH changes the stability of a protein structure and can cause its denaturation.
Here is a simple answer (message me if you want the more complex version):
So enzymes are able to act on their specific substrates because of their shape. When that shape is distorted, called denaturing, they are no longer active. Now changes in pH are really changes in H+ concentration. This affects individual amino acids in the enzyme, possibly disrupting bonds that define the shape. This can happen in too high or too low pHs for that specific enzyme.
a change in pH alters the availability of H+, OH-, or other ions, thereby disrupting the hydrogen bonding and ionic bonds that maintain protein shape.
Yes, proteins are susceptible to denaturation by both high and low pH extremes as well as temperature extremes.
Temperature and enzymes. A good temperature example is the proteins in egg whites denaturing when exposed to heat. Specific enzymes denature specific proteins: lactase (an enzyme) denatures lactose (protein present in dairy products). Protein denaturation can be caused by a number of different factors. These include heat exposure, introduction to acidic surroundings, and exposure to high energy electromagnetic radiation.
if u mean 'what are the factors that denature enzymes?' the answer is:--------- changes in pH and an increase in temperature
Temperature and pH are the two factors that can cause enzymes to denature.
Extreme heat, high or low pH, ionization of liquid medium, and a change in environment. The last one needs a little more explanation. If a protein is meant for a liquid-liquid environment, and it is brought into an air-liquid environment, it may denature. Proteins form because of the folds created from hydrophilic and hydrophobic folding. If there is no water in which these bonds form, the protein will denature.
Many things can denature proteins. Proteins have different optimal ranges in pH and temperature and outside of these optima then the enzyme will not work as well or at all. Also specific detergents will denature an enzyme depending on the enzyme.
You would die. The blood proteins would denature and stop functioning.
Denature
do you mean pH? If the pH in our body is low enough it will denature the proteins that are involved in all our metabolic processes as well as the tissue we are built out of. Denature means to break apart.
Yes it can. Since enzymes are proteins, changes such as pH level, salinity, and even temperature can denature the proteins rendering them incapable of performing it's function because the shape has been altered.
Simply put, enzymes are proteins and proteins can denature (break) under the right conditions. These conditions would include temperature and pH (however these are not the only factors) and so the changing of pH could definitely affect hexolkinase (or did you mean hexokinase? which would make more sense).
Yes, denaturation of proteins is a function of the stomach. The stomach secretes hydrochloric acid that helps to lower the pH of the stomach, which denatures proteins. This denaturation process makes the proteins more susceptible to the action of digestive enzymes, facilitating their breakdown into smaller peptides and amino acids.
Temperature, pH, organic solvent, mechanical forces
Temperature and enzymes. A good temperature example is the proteins in egg whites denaturing when exposed to heat. Specific enzymes denature specific proteins: lactase (an enzyme) denatures lactose (protein present in dairy products). Protein denaturation can be caused by a number of different factors. These include heat exposure, introduction to acidic surroundings, and exposure to high energy electromagnetic radiation.
Because proteins denature, or break down, outside of the optimal pH range. When a protein denatures, it loses its shape and is unable to bind with its substrate, therefore making it unable to function.
If denature = dead then at high temperatures, high alcohol content, high/low pH
if u mean 'what are the factors that denature enzymes?' the answer is:--------- changes in pH and an increase in temperature
Temperature and pH are the two factors that can cause enzymes to denature.