No
According to the Mayo Clinic web site the Mayo brothers were Protestant. They worked with Catholic nuns in the beginning in Rochester so I think people assumed they must have been Catholic as well.Also, the name Mayo sounds like the family would be Irish as there is a county Mayo in Ireland. The father of the Mayo brothers immigrated from England, however.
The Mayo scissors were invented by Charles Horace Mayo and William Charles Mayo. They were brothers, doctors, and the founders of the famous Mayo Clinic.
Charles and William
Katherine Mayo died in 1940.
Bernard Mayo died in 2000.
Christine Mayo died in 1963.
Eileen Mayo died in 1994.
Alfredo Mayo died in 1985.
Gerald of Mayo died in 731.
Frank Mayo died in 1896.
Jeff Mayo died in 1998.