Novocain blocks calcium channels. Voltage-dependent calcium channels are a group of ion channels found in the membrane of excitable cells such as the axons of neurons and glial cells.
they are important in the nervous system they lead to chnages in sodium and calcium concentrations in cells they open or close in response to a chemical signal
In muscle cells the inward current is a sodium + calcium flow through acetycholine activated channels as well as through voltage sensitive calcium channels.
integral protein channels
An action potential is propagated in a neuron through the activation of various voltage-gated and ligand-gated ion channels. Examples include sodium and calcium channels and nicotinic-acetylcholine receptors.
coupled
Blocking sodium ion channels reduces the uptake of water from the lumen of the intenstine into the epithelial cells of the villus due to osmosis. Water, therefore, remains in the intestine and this causes watery faeces/diarrhoea
When sodium channels are not active, it means that the capability of neurons to send the electronic signals in the body weakens. Neurons are nerve cells that communicate by passing Na+ and K+ ions.
causes chemically gated sodium channels to open
sodium channels
Novocain blocks calcium channels. Voltage-dependent calcium channels are a group of ion channels found in the membrane of excitable cells such as the axons of neurons and glial cells.
Sodium
they are important in the nervous system they lead to chnages in sodium and calcium concentrations in cells they open or close in response to a chemical signal
In muscle cells the inward current is a sodium + calcium flow through acetycholine activated channels as well as through voltage sensitive calcium channels.
It results from the opening of voltage-gated sodium ion channels, causing an influx of sodium ions (influx of positively-charged ions), depolarizing the neuronal membrane.
integral protein channels
An action potential is propagated in a neuron through the activation of various voltage-gated and ligand-gated ion channels. Examples include sodium and calcium channels and nicotinic-acetylcholine receptors.