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Aspirin (acetlysalicylic acid) is an irreversible inhibitor of the cyclo-oxygenase (COX-I and COX-II) enzymes which are responsible for the conversion of arachidonic acid into the prostaglandins. It is supposed that this happens due to the acetylation effects of aspirin.

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Q: Does Aspirin inhibit vasoconstriction and platelet aggregation by blocking synthesis of the prostaglandin?
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