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A larger LD indicates a less toxic substance, because it takes more of the substance to kill.
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∙ 12y ago
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How fast can chlorine gas kill someone?
The LD50 (the dose that'll kill half the people who take it) of potassium ferricyanide is 2970mg/kg, which is very nearly the same as the LD50 of table salt. I wouldn't recommend eating any of it - it'll make you sick as a dog if you do - but it won't kill you.
What is the LD50 of ethanol?
After some pretty extensive searching I found 25800 mg/kg-1 for a rat, that's what I used for my lab write-up so I hope it's right.
Lethal dose of potassium chloride?
Orally, KCl is toxic in excess; the LD50 is around 2500 mg/kg (meaning that a lethal dose for 50% of people weighing 75 kg (165 lb) is about 190 g (6.7 ounces), or about 38 teaspoons). Table salt is about as toxic. Intravenously this is reduced to just over 100 mg/kg, but of more concern are its severe effects on the cardiac muscles; high doses can cause cardiac arrest and rapid death, ergo its aforementioned use as the third and final drug delivered in the lethal injection process. SOURCE CITED :: http://en.wikipedia.org/wiki/Potassium_chloride
What is the most dangerous LD 50 value 500 or 17.5?
An LD50 value of 17.5 milligrams would be considered far more dangerous than an LD50 value of 500 milligrams. The LD50 value for any drug or other chemical compound is the minimum lethal dose that kills 50% of test subjects (tests are usually conducted on rats and mice). Thus the lower the value, the more toxic the drug.
What is the difference between a toxin and poison?
The way that toxic materials are defined is by how well they kill rats. This is called the "Median Lethal Dose" or LD50. It is usually expressed as "LD50, Oral, Rat" meaning that the subjects were specially bred, white, Norway rats and the dose was given by mouth. The dose is presented as milligrams per kilogram of rat.The U.S. EPA and OSHA define a toxin as a substance that has an LD50 of 500 mg/Kg or less. Acutely toxic materials have an LD50 of 50 mg/Kg or less.The U.S. DOT defines poison as a substance with an LD50 of 200 mg/kg or less.
Why is the LD50 of a mouse different from a human's LD50?
ld50 for lamotrigine
Is14 butanediol the same as propylene glycol as far as ingesting one or the?
No. 1,4-butanediol is significantly more toxic. The MSDS for propylene glycol lists an oral LD50 of 20g/kg in rats, while that for 1,4-butanediol says its LD50 for rats is 1.5g/kg.
Why would cockarocahes survive a nuclear blast?
Insects have higher LD50 for radiation exposure than mammals. LD50 is defined as the dose of something toxic that results in 50% fatality in the exposed group. However insects would have similar problems to mammals surviving the thermal effects.
What is the LD50 of pure silver?
LD50 relates to the compound/element, not to poisoning - it is the LD50 of mercury. It varies depending on route of exposure and the animal tested but it is around 1 to 15 mg/kg body-weight.
What is the toxic dose of oxycodone?
105 mgs per day is the average dose. Sources rxlist.com Drugs.com
Are some drugs less dangerous then others?
In short, Yes. In long, Yes the LD50 (the lethal dose for 50% of the tested population) is the measure of how toxic a drug is... for instance THC (the active compound in cannabis) has an LD50 (oral) of 1270 milligrams per kilo of body weight, whereas the LD50 (oral) of Diamorphine (aka heroin) is as low as 2.6mg/kilo, making it 489 times more toxic than THC. Componding this is that the pharmokinetics of each drug differ significantly depending on the method of administration, meaning that a safe dose for ingestion (where only maybe 30% at most of the drug will reach your bloodstream) is a lot higher than for rectal/vaginal routes (suppositories or enema) and intramuscular injections which themselves would need a higher dose than an intraveinous injection.
What do people do to animals during animal experimentation?
The two most common tests are the LD50 test and the Draize test. In the LD50 test, which tests how toxic something is, a group of animals is forced into a small corral along with a toxic substance and a timer is started to see how long it taked for 50% of the animals to die. The Draize test tests how irritating something it using rabbits. Rabbits eyes are clipped open and a substance is forced into them and irritation is measured.
What is a Poison?
A poisonous mushroom is a poisonous mushroom
What is the ld50 rating and why is it so important?
It's a measure of how toxic a substance is. LD50 stands for lethal dose 50--it's the amount that, when given to a group of laboratory rats, will kill 50% of them. Often expressed in milligrams per kilogram of body weight (since it usually takes more poison to kill a bigger animal).
Is Lysol a poison?
"Poison" is defined by the Department of Transportation (DOT) as anything with an LD50 Oral Rat less than 200 mg/Kg. Toxic is defined by the Environmental Protection Agency (EPA) and Occupational Safety and Health Administration (OSHA) as anything with an LD50 Oral Rat less than 500 mg/Kg and acutely toxic substances have an LD50 Oral Rat less than 50 mg/Kg. After scanning several MSDSs at the site below, it appears that none of the Lysol(R) brand products would, by themselves, be toxic by definition. Some preparations do contain phenol which has an LD50 Oral Rat of 317 mg/Kg. Phenol is, therefore, toxic by definition but the formula that contains a small percent of phenol would not necessarily be toxic. Probably the greatest risk is not from being poisoned, but from the corrosive effect from those formulas that contain sodium or potassium hydroxide. There are a few MSDSs that warn against inducing vomiting if ingested because of the tissue damage that would result. Find your product and read the MSDS. Everything can kill you...there was a woman who recently died from drinking too much water. It is good advice to avoid drinking Lysol.
