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Being overtired itself doesnt stress the vocal folds (cords). However, general stress (which being over tired can relate to) can effect use of the vocal folds and how stressed they are.

Every day usage damages the vocal folds and this daily damage from vibration is repaired primarily while sleeping. So, lack of sleep will reduce the repair time as well as reduce the body's efficiency in repairing damage.

see www.ncvs.org for more info like this.

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Q: Does being over tired stress vocal cords?
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