Extravascular hemolysis occurs when degradation of rbc's by macrophages occur in the liver and spleen. The most common form of extravascular hemolysis occurs in hemolytic anemia.
Blood
spleen is one of our body organ.organ means collection of tissue.it filters foreign materials &produce lympocytes.
The spleen
The spleen identifies "old" erythrocytes (RBCs) and destroys them. The life of an RBC is around 120 days.
Spleen
True. When erythrocytes are no longer useful they are destroyed by macrophages in the spleen liver and bone marrow.
When erythrocytes are no longer useful they are destroyed by macrophages in the spleen, liver, and bone marrow.
The spleen.
Extravascular hemolysis occurs when degradation of rbc's by macrophages occur in the liver and spleen. The most common form of extravascular hemolysis occurs in hemolytic anemia.
Blood
spleen is a secondary lymphoid organ. let me explain this in simple word. spleen has abundant macrophages, which can sense abnormalities of red blood cells(RBC) and platelet. abnormal and old RBC and platelet are removed from circulation by spleen. so many conditions in which spleen gets bigger that would remove more platelet even if they are normal, leading to decrease the count of platelet.
Presented by APCs as MHC-exogenous peptide complex
The spleen is not necessary for life but does have important functions: 1. Defense -macrophages lining sinusoids of spleen remove microorganisms from blood and phagocytose (eat) them. 2. Hematopoiesis -monocytes (white blood cell) and lymphocytes (white blood cell) complete their development in the spleen. 3. Red blood cell and platelet destruction-macrophages remove worn-out RBCs and imperfect platelets and destroy them by phagocytosis (eating); also salvage iron and globin from destroyed RBCs 4. Blood reservoir -pulp of spleen and its sinuses store blood for when you really need extra blood. If you noticed a "stitch" in your side when running hard, that is the spleen adding blood to the system so you will get oxygen.
Lymph nodes are located along lymphatic pathways, and contain lymphocytes and macrophages, which destroy invading microorganisms. They remove and destroy potentially harmful foreign particles from the lymph through phagocytosis by macrophages. They are also the centers for the production of lymphocytes that act against foreign particles.Lymph nodes are located along lymphatic pathways, and contain lymphocytes and macrophages, which destroy invading microorganisms.
spleen
B Cells and macrophages