S phase
The sister chromatids first appear in the S phase of the cell cycle.
Chromosomes first appear to be double during the S phase of the cell cycle when DNA replication occurs. This results in two identical sister chromatids joined by a centromere in preparation for cell division.
metaphase
The chromatids are first separated from each other during the anaphase stage of meiosis.
During mitosis, chromosomes replicate by first unwinding and duplicating their DNA. Each chromosome then forms a sister chromatid, creating two identical copies. These sister chromatids are held together at a region called the centromere. Finally, during cell division, the sister chromatids separate and move to opposite ends of the cell, ensuring that each new cell receives a complete set of chromosomes.
At the center! Sister chromatids are identical copies of a given chromosome. before the cell divides it must first copy the entire genome. sister chromatids are shaped like > and < and are linked at the centromere. The tips are called telomeres.
A chromatid really only exists during the first two stages of mitosis(prophase and metaphase). This is when the DNA has been replicated and the chromosomes essentially is composed of 2 identical segments.
Yes, in both mitosis and meiosis, the individual chromosomes move apart during cell division. In mitosis, the sister chromatids of each chromosome separate and move to opposite poles of the cell, while in meiosis, homologous chromosomes separate in the first division and sister chromatids separate in the second division.
In Meiosis I: Separates homologous chromosomes In Meiosis II: Separates sister chromatids
The chromatids can first be seen under a light microscope during the metaphase stage of mitosis, when they line up along the cell's equator.
The stage of mitosis when the chromatids are visible is the metaphase stage. During metaphase, the duplicated chromosomes line up along the center of the cell, with their chromatids attached to the spindle fibers.
During the first stage of anaphase the kinetochore microtubules retract pulling the two sister chromatids apart towards the poles. During the second stage of anaphase the mitotic poles that is mared by the centrosomes themselves separate by the elongation of a specific type of non-kinetochore microtubule called as the polar microtubule.