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If you're referring to running a sterilizer, it won't help a fish that already has ick.

But a sterilizer is cheap insurance and will help prevent future outbreaks of ick and other diseases.

If you're referring to cleaning out a tank with bleach and then reassembling it, this will not help a fish that already has ick. But if your fish have already died then you MUST sterilize the tank before adding other fish. The ick can remain the water and re-infect new fish.

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Q: Fish tank sterilization will or will not help ick in fish?
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